Description

(2,2,3,3-Tetramethylcyclopropyl)Methanamine Hydrochloride is a high-purity, synthetically valuable amine hydrochloride salt featuring a unique, sterically hindered cyclopropyl scaffold. This compound matters as a critical chiral building block and intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures with precise stereochemistry. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, where its rigid structure can impart significant metabolic stability and biological activity.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapeutics.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the cyclopropyl group enhances compound stability and efficacy.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty monomers and polymers with unique thermal and mechanical properties.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Process R&D: A valuable substrate for contract research organizations (CROs) and process chemistry teams scaling up novel synthetic routes.

Basic Information

Product Name	(2,2,3,3-Tetramethylcyclopropyl)Methanamine Hydrochloride
CAS No.	67358-15-0
Molecular Formula	C9H18ClN
Molecular Weight	175.70 g/mol
Synonyms	1-(2,2,3,3-Tetramethylcyclopropyl)methanamine hydrochloride; (2,2,3,3-Tetramethylcyclopropane)methylamine hydrochloride; 1-Aminomethyl-2,2,3,3-tetramethylcyclopropane hydrochloride; Tetramethylcyclopropylmethylamine HCl; Cyclopropanemethanamine, 2,2,3,3-tetramethyl-, hydrochloride; 67358-15-0; (2,2,3,3-Tetramethylcyclopropyl)methylamine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of (2,2,3,3-Tetramethylcyclopropyl)Methanamine Hydrochloride is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for critical R&D and scale-up applications. A detailed Certificate of Analysis (COA) including results for assay, chiral purity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.