Description

cis-4-(Benzyloxycarbonyl)Cyclohexylammonium Tosylate is a high-purity, protected amino acid derivative used as a critical building block in advanced organic synthesis. This compound is essential for the controlled introduction of the cis-4-aminocyclohexyl moiety into complex molecular architectures, ensuring precise stereochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Peptide Chemistry: Serves as a protected amino acid derivative for solid-phase and solution-phase peptide synthesis, enabling the incorporation of constrained cyclohexylalanine analogs.
• Chemical Research: Used in academic and industrial R&D for exploring new synthetic methodologies and constructing molecular libraries for screening.
• Agrochemical Development: Acts as a precursor in the design of novel herbicides and fungicides with specific stereochemical requirements.
• Material Science: Potential monomer or modifier in the synthesis of specialized polymers with unique structural properties.

Basic Information

Product Name	cis-4-(Benzyloxycarbonyl)Cyclohexylammonium Tosylate
CAS No.	67299-45-0
Molecular Formula	C21H27NO5S
Molecular Weight	405.51 g/mol
Synonyms	cis-4-(Cbz-Amino)Cyclohexylammonium Tosylate; (1r,4r)-4-(((Benzyloxy)carbonyl)amino)cyclohexan-1-aminium 4-methylbenzenesulfonate; Cbz-cis-4-Aminocyclohexylamine Tosylate Salt; Z-cis-4-Aminocyclohexylammonium Tosylate; (cis)-4-[(Benzyloxycarbonyl)amino]cyclohexylammonium p-Toluenesulfonate; N-[(1r,4r)-4-Aminocyclohexyl]carbamic Acid Benzyl Ester Tosylate; 4-(N-Cbz-amino)-cis-cyclohexylamine Tosylate
EINECS	Contact for details

Quality Control

Our cis-4-(Benzyloxycarbonyl)Cyclohexylammonium Tosylate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformity to customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% cis-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.