Description

2-Chloroacetoacetamide is a versatile halogenated acetoacetamide derivative, a key building block in organic synthesis. Its reactive chloro and carbonyl groups make it a crucial intermediate for constructing complex heterocyclic and pharmaceutical compounds. This high-purity intermediate is essential for manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable synthesis pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing pyrazole, pyrimidine, and other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the manufacturing of herbicides, fungicides, and insecticides, where its structure serves as a core component for bioactive molecules.
• Fine Chemical Production: Employed in the synthesis of dyes, pigments, and other specialty chemicals requiring functionalized acetamide structures.
• Research & Development: Serves as a valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and novel compound libraries.
• Chemical Cross-linking Agent: Its reactive sites can be utilized in polymer chemistry and material science for cross-linking applications.

Basic Information

Product Name	2-Chloroacetoacetamide
CAS No.	67271-66-3
Molecular Formula	C4H6ClNO2
Molecular Weight	135.55 g/mol
Synonyms	2-Chloro-3-oxobutanamide; Chloroacetoacetamide; 2-Chloroacetoacetamide; 3-Oxo-2-chlorobutanamide; Acetoacetamide, 2-chloro-; α-Chloroacetoacetamide; NSC 403796; Butanamide, 2-chloro-3-oxo-
EINECS	Contact for details

Quality Control

Our 2-Chloroacetoacetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.