Description

Diethyl-3-Chloro-2-Oxopropyl Phosphonate is a versatile organophosphorus compound, specifically a phosphonate ester, that serves as a critical building block in advanced organic synthesis. Its primary value lies in its bifunctional reactivity, featuring both a chloro and an oxo (ketone) group, making it an excellent precursor for the synthesis of complex molecules. This intermediate is particularly essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require high-purity, reliable starting materials for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), including potential antiviral and antibacterial agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, insecticides, and plant growth regulators.
• Chemical Research & Development: A valuable reagent for constructing complex molecular architectures in academic and industrial R&D laboratories.
• Material Science: Potential intermediate for the synthesis of specialized polymers, ligands, or flame retardants.
• Cross-Coupling Reactions: Acts as a substrate in Horner-Wadsworth-Emmons (HWE) olefination reactions to form α,β-unsaturated carbonyl compounds.

Basic Information

Product Name	Diethyl-3-Chloro-2-Oxopropyl Phosphonate
CAS No.	67257-29-8
Molecular Formula	C7H14ClO4P
Molecular Weight	228.61 g/mol
Synonyms	Diethyl (3-Chloro-2-oxopropyl)phosphonate; 3-Chloro-2-oxopropylphosphonic Acid Diethyl Ester; Diethyl 3-Chloroacetonylphosphonate; (3-Chloro-2-oxopropyl)phosphonic Acid Diethyl Ester; 67257-29-8; Phosphonic Acid, (3-Chloro-2-oxopropyl)-, Diethyl Ester; Diethyl 3-Chloro-2-oxopropylphosphonate
EINECS	Contact for details

Quality Control

Our Diethyl-3-Chloro-2-Oxopropyl Phosphonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.