Description

(1R,4Aβ)-8Aα-Acetoxymethyl-5β-[2-(3-Furyl)Ethyl]-2,3,4A,5,6,7,8,8A-Octahydro-8β-Hydroxy-5,6α-Dimethylspiro[Naphthalene-1(4H),2'-Oxiran]-4-One is a complex, high-purity synthetic intermediate characterized by its unique spirocyclic and oxirane (epoxide) ring structure. This compound matters as a versatile chiral building block for advanced organic synthesis, enabling the construction of intricate molecular architectures with precise stereochemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the multi-step synthesis of potential drug candidates, particularly in oncology, neurology, and anti-infective research.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where its complex structure can contribute to unique modes of action.
• Academic & Process Chemistry: Employed in methodological studies for novel cyclization, epoxidation, or asymmetric synthesis routes.
• Fine Chemical Synthesis: Acts as a building block for creating specialty chemicals with specific optical activities for advanced material science.
• Contract Research & Manufacturing (CRAM): Supplied to organizations requiring custom synthesis services for client-specific projects.

Basic Information

Product Name	(1R,4Aβ)-8Aα-Acetoxymethyl-5β-[2-(3-Furyl)Ethyl]-2,3,4A,5,6,7,8,8A-Octahydro-8β-Hydroxy-5,6α-Dimethylspiro[Naphthalene-1(4H),2'-Oxiran]-4-One
CAS No.	67244-39-7
Molecular Formula	C23H30O6
Molecular Weight	402.48 g/mol
Synonyms	8aα-Acetoxymethyl-5β-[2-(3-furyl)ethyl]-2,3,4a,5,6,7,8,8a-octahydro-8β-hydroxy-5,6α-dimethylspiro[naphthalene-1(4H),2'-oxiran]-4-one; Spiro[oxirane-2,1'(4'H)-naphthalene] derivative; (1R,4aβ,5β,6α,8aα,8β)-rel-8a-(Acetoxymethyl)-5-[2-(3-furanyl)ethyl]octahydro-8-hydroxy-5,6-dimethylspiro[naphthalene-1(4H),2'-oxiran]-4-one; CAS 67244-39-7.
EINECS	Contact for details

Quality Control

Our high-purity synthetic intermediate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.