Description

(1R,4Aβ)-8Aα-Acetoxymethyl-5β-[2-(3-Furyl)Ethyl]-3,4,4A,6,7,8A-Hexahydro-4α-Hydroxy-5,6α-Dimethylspiro[Naphthalene-1(2H),2'-Oxiran]-8(5H)-One is a complex, high-purity synthetic intermediate characterized by its unique spirocyclic and furan-containing structure. This compound is of significant value in advanced organic synthesis, particularly for constructing intricate molecular frameworks found in active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily sought by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the research and development of new therapeutic agents, particularly for complex small-molecule drugs.
• Agrochemical Synthesis: Used in the synthesis of advanced crop protection agents, leveraging its unique structure for bioactivity.
• Fine Chemical Production: Acts as a precursor in the manufacture of specialty chemicals, flavors, and fragrances requiring sophisticated stereochemistry.
• Academic & Industrial Research: A valuable tool for methodological studies in organic chemistry, including catalysis and stereoselective synthesis.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Item	Details
Product Name	(1R,4Aβ)-8Aα-Acetoxymethyl-5β-[2-(3-Furyl)Ethyl]-3,4,4A,6,7,8A-Hexahydro-4α-Hydroxy-5,6α-Dimethylspiro[Naphthalene-1(2H),2'-Oxiran]-8(5H)-One
CAS No.	67233-27-6
Molecular Formula	C23H30O6
Molecular Weight	402.48 g/mol
Synonyms	8aα-Acetoxymethyl-5β-[2-(3-furyl)ethyl]-3,4,4a,6,7,8a-hexahydro-4α-hydroxy-5,6α-dimethylspiro[naphthalene-1(2H),2'-oxiran]-8(5H)-one; Spiro[oxirane-2,1'(2'H)-naphthalene] derivative; CAS 67233-27-6; (1R,4aβ,5β,6α,8aα)-rel-8a-(Acetoxymethyl)-5-[2-(3-furanyl)ethyl]-3,4,4a,6,7,8a-hexahydro-4-hydroxy-5,6-dimethyl-spiro[naphthalene-1(2H),2'-oxiran]-8-one; Furan-containing spirocyclic epoxide.
EINECS	Contact for details

Quality Control

Our (1R,4Aβ)-8Aα-Acetoxymethyl-5β-[2-(3-Furyl)Ethyl]-3,4,4A,6,7,8A-Hexahydro-4α-Hydroxy-5,6α-Dimethylspiro[Naphthalene-1(2H),2'-Oxiran]-8(5H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for advanced synthetic intermediates. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be sensitive to moisture and prolonged exposure to elevated temperatures.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.