Description

(1R,8Aα)-1,3,4,5,6,7,8,8A-Octahydro-6β-Hydroxy-1,6-Dimethyl-2H-4Aα,1-(Epoxymethano)Naphthalen-10-One is a high-purity, complex sesquiterpenoid compound with a unique epoxide and ketone functional group architecture. This specific stereochemistry is critical for its role as a key synthetic intermediate and reference standard in advanced organic synthesis. It is essential for research and development chemists in the pharmaceutical and fine chemical industries who require precise molecular building blocks for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral precursor for the synthesis of novel therapeutic agents, particularly in steroid and terpenoid-based drug development.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex natural products, fragrances, and specialty chemicals where its rigid polycyclic structure provides stereochemical control.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development, validation, and impurity profiling in related chemical processes.
• Academic & Industrial Research: A valuable compound for studying structure-activity relationships (SAR), reaction mechanisms, and catalysis involving epoxide and ketone functionalities.
• Agrochemical Research: Potential intermediate in the development of new bioactive compounds for crop protection, leveraging its complex terpenoid backbone.

Basic Information

Item	Details
Product Name	(1R,8Aα)-1,3,4,5,6,7,8,8A-Octahydro-6β-Hydroxy-1,6-Dimethyl-2H-4Aα,1-(Epoxymethano)Naphthalen-10-One
CAS No.	67191-89-3
Molecular Formula	C15H22O3
Molecular Weight	250.33 g/mol
Synonyms	6β-Hydroxy-1,6-dimethyl-4aα,1-(epoxymethano)-1,3,4,5,6,7,8,8a-octahydro-2H-naphthalen-10-one; (1R,4aS,6R,8aS)-6-Hydroxy-1,6-dimethyl-4a,5,6,7,8,8a-hexahydro-1H-naphtho[1,8a-b]oxiren-3(4aH)-one; Aromadendrene oxide derivative; Sesquiterpenoid epoxide ketone; 1,6-Dimethyl-6-hydroxy-4a,1-epoxymethano-octahydronaphthalen-10-one
EINECS	Contact for details

Quality Control

Our (1R,8Aα)-1,3,4,5,6,7,8,8A-Octahydro-6β-Hydroxy-1,6-Dimethyl-2H-4Aα,1-(Epoxymethano)Naphthalen-10-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for assay, related substances, and chiral purity are provided and available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be sensitive to prolonged exposure to heat and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.