Description

n-Benzylquininium Chloride is a quaternary ammonium salt derivative of the natural alkaloid quinine. This compound is valued as a versatile chiral phase-transfer catalyst (PTC) and a key intermediate in asymmetric synthesis. It is primarily utilized by research institutions and industrial R&D departments focused on developing pharmaceuticals, agrochemicals, and specialty chemicals where high enantioselectivity is critical.

Application

• As a chiral phase-transfer catalyst (PTC) for enantioselective alkylation, Michael addition, and other carbon-carbon bond-forming reactions.
• As a key chiral auxiliary or resolving agent in the synthesis of optically active pharmaceutical intermediates.
• For the development of novel asymmetric synthesis methodologies in academic and industrial research laboratories.
• In the preparation of specialty chemicals and fine chemicals requiring high enantiomeric purity.
• As a reference standard or analytical reagent in chromatographic method development for chiral separation.

Basic Information

Product Name	n-Benzylquininium Chloride
CAS No.	67174-25-8
Molecular Formula	C27H31ClN2O2
Molecular Weight	451.00 g/mol
Synonyms	Benzylquininium Chloride; N-Benzylquininium Chloride; Quininium, N-benzyl-, chloride; (8α,9R)-N-Benzyl-6'-methoxycinchonan-9-ol Chloride; Cinchonan-9-ol, N-benzyl-, chloride, (8α,9R)-; N-Benzylquinidine Chloride (common misnomer, check isomer); Chiral Phase-Transfer Catalyst PTC; BQ-Cl
EINECS	Contact for details

Quality Control

Our n-Benzylquininium Chloride is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided, typically including data from HPLC, NMR, and specific rotation measurements to confirm its suitability as a high-performance chiral catalyst.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.