Description

1,5,9-Triazacyclododecane, Trihydrochloride is a high-purity, nitrogen-containing macrocyclic compound supplied as its stable trihydrochloride salt. This specialized chemical serves as a versatile and crucial chelating ligand and building block in advanced research and industrial synthesis. It is primarily utilized by pharmaceutical researchers, material scientists, and catalyst developers working on metal complexes, supramolecular chemistry, and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel macrocyclic drug candidates and diagnostic agents.
• Catalyst Ligand: Acts as a tridentate ligand for transition metals (e.g., Cu, Ni, Co) in homogeneous catalysis and oxidation reactions.
• Supramolecular Chemistry: Used in the construction of molecular cages, hosts, and complex 3D architectures due to its rigid cyclic structure.
• Metal Ion Sequestration: Employed in research for binding and removing specific metal ions from solutions.
• Polymer Modification: Incorporated into polymer backbones to impart metal-binding properties or create functional materials.
• Chemical Research: Fundamental reagent in academic and industrial R&D for exploring new coordination chemistry and reaction pathways.

Basic Information

Product Name	1,5,9-Triazacyclododecane, Trihydrochloride
CAS No.	67162-92-9
Molecular Formula	C9H24Cl3N3
Molecular Weight	288.66 g/mol
Synonyms	1,5,9-Triazacyclododecane trihydrochloride; 1,5,9-Triazacyclododecane hydrochloride; 1,5,9-Triazacyclododecane HCl; [12]aneN3 trihydrochloride; 1,5,9-Triazacyclododecane, hydrochloride (1:3); 1,4,7-Triazacyclononane analogue (expanded ring); Triazacyclododecane trihydrochloride; TACD trihydrochloride
EINECS	Contact for details

Quality Control

Our 1,5,9-Triazacyclododecane, Trihydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP and ISO compliant production for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the original container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.