Description

2,8-Dichloro-Quinazoline is a versatile and high-value halogenated heterocyclic building block essential for advanced organic synthesis. Its core value lies in its dual reactive sites, which enable precise functionalization to create complex molecular architectures. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, anticancer agents, and other biologically active quinazoline derivatives.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides, leveraging the quinazoline scaffold's bioactivity.
• Material Science Research: Serves as a building block for creating organic electronic materials, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Biology & Proteomics: Employed in the design and synthesis of chemical probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing client-specific compounds.

Basic Information

Product Name	2,8-Dichloro-Quinazoline
CAS No.	67092-20-0
Molecular Formula	C8H4Cl2N2
Molecular Weight	199.04 g/mol
Synonyms	2,8-Dichloroquinazoline; Quinazoline, 2,8-dichloro-; 2,8-DCQ; 2,8-Dichloro-benzo[d]pyrimidine
EINECS	Contact for details

Quality Control

Our 2,8-Dichloro-Quinazoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.