Description

2,6-Dichloroquinazoline CAS NO 67092-18-6 is a versatile and high-value halogenated heterocyclic building block essential for advanced organic synthesis. Its primary commercial value lies in its role as a key intermediate for constructing complex molecules in pharmaceutical and agrochemical research and development. This compound is particularly critical for medicinal chemists and process development scientists working on kinase inhibitors, anticancer agents, and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, particularly kinase inhibitors and targeted cancer therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the quinazoline core's bioactivity.
• Material Science Research: Serves as a building block for creating organic electronic materials, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Biology & Proteomics: Employed in the design and synthesis of chemical probes and affinity tags for studying protein function and interactions.
• Academic & Contract Research: A fundamental reagent for novel heterocyclic chemistry research in university and CRO (Contract Research Organization) laboratories.
• Custom Synthesis & Scale-up: Supplied for custom manufacturing projects, from milligram-scale discovery support to kilogram-scale process development.

Basic Information

Product Name	2,6-Dichloroquinazoline
CAS No.	67092-18-6
Molecular Formula	C8H4Cl2N2
Molecular Weight	199.04 g/mol
Synonyms	2,6-Dichloro-quinazoline; Quinazoline, 2,6-dichloro-; 2,6-Dichloroquinazoline; 67092-18-6; 2,6-Dichloro-1,3-diazanaphthalene; NSC 403079; BRN 0129362; AKOS005258495
EINECS	Contact for details

Quality Control

Our 2,6-Dichloroquinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.