Description

Gm1 Pentasaccharide Sodium Salt CAS NO 67063-78-9 is a high-purity, synthetic carbohydrate derivative representing the core pentasaccharide structure of the GM1 ganglioside. This compound is a critical biochemical tool and intermediate for advanced research in glycobiology and neuroscience. It is primarily utilized by pharmaceutical R&D teams, diagnostic developers, and academic researchers focused on studying ganglioside-related biological pathways, developing targeted therapies, and creating novel diagnostic assays.

Application

• Biochemical Research & Standard: Serves as a reference standard and key intermediate for studying GM1 ganglioside function, cell signaling, and carbohydrate-protein interactions.
• Pharmaceutical Development: Used as a building block or active pharmaceutical ingredient (API) intermediate in the development of novel therapeutics targeting neurological disorders, cancer, and bacterial toxins.
• Diagnostic Reagent Manufacturing: Employed in the synthesis of probes, conjugates, and assay components for detecting antibodies, toxins, or specific biomarkers in clinical and research settings.
• Glycoconjugate Synthesis: Acts as a crucial precursor for the chemical and enzymatic synthesis of more complex gangliosides, glycoproteins, or neoglycoconjugates.
• Neuroscience Studies: Applied in research models to investigate neurotrophic effects, neuronal development, and the role of gangliosides in neurodegenerative diseases.
• Vaccine Adjuvant Research: Explored for its immunomodulatory properties in the development of conjugate vaccines and novel adjuvant systems.

Basic Information

Product Name	Gm1 Pentasaccharide Sodium Salt
CAS No.	67063-78-9
Molecular Formula	C31H52N2O23Na
Molecular Weight	827.73 g/mol
Synonyms	GM1 Pentasaccharide, Sodium Salt; Ganglioside GM1 Oligosaccharide Sodium Salt; II3Neu5Ac-Gg4 Sodium Salt; β-D-Gal-(1->3)-β-D-GalNAc-(1->4)-[α-D-Neu5Ac-(2->3)]-β-D-Gal-(1->4)-β-D-Glc Sodium Salt; Asialo-GM1 Pentasaccharide derivative; Neu5Ac-α-2,3-Gal-β-1,3-GalNAc-β-1,4-Gal-β-1,4-Glc Sodium Salt; GM1-OS Sodium Salt
EINECS	Contact for details

Quality Control

Our Gm1 Pentasaccharide Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Bacterial Endotoxins	< 10 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.