Description

9-Chloro-7-Fluoro-1,2,3,4-Tetrahydro-Acridine is a high-value, halogenated heterocyclic compound with the CAS registry number 66949-81-3. This molecule serves as a critical advanced pharmaceutical intermediate and a versatile scaffold in medicinal chemistry research. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients. Its unique structure makes it a key building block for developing compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel acridine-based drug candidates, particularly for central nervous system (CNS) and anti-infective applications.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as an intermediate in the research and production of new-generation pesticides and herbicides.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex heterocyclic systems and functional materials.
• Fluorescent Probe Synthesis: Utilized in the development of acridine-derived dyes and probes for biochemical and diagnostic applications.

Basic Information

Item	Details
Product Name	9-Chloro-7-Fluoro-1,2,3,4-Tetrahydro-Acridine
CAS No.	66949-81-3
Molecular Formula	C₁₃H₁₁ClFN
Molecular Weight	235.69 g/mol
Synonyms	9-Chloro-7-fluoro-1,2,3,4-tetrahydroacridine; 7-Fluoro-9-chloro-1,2,3,4-tetrahydroacridine; 1,2,3,4-Tetrahydro-9-chloro-7-fluoroacridine; Acridine, 9-chloro-7-fluoro-1,2,3,4-tetrahydro-; 66949-81-3; 9-Cl-7-F-THA
EINECS	Contact for details

Quality Control

Our 9-Chloro-7-Fluoro-1,2,3,4-Tetrahydro-Acridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.