Description

2-(4-Amino-2-Bromophenyl)Acetic Acid is a specialized brominated aromatic acetic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino and a bromo substituent, makes it a versatile intermediate for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop new active compounds.

Application

This high-purity intermediate is designed for demanding synthetic applications, primarily in regulated industries.

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Building block for developing new-generation herbicides and fungicides with specific modes of action.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions, such as Buchwald-Hartwig amination.
• Material Science Research: Intermediate for synthesizing functionalized monomers aimed at producing advanced polymers with specific optical or electronic properties.
• Chemical Research & Development: A versatile starting material for academic and industrial research into new heterocyclic compounds and fine chemicals.

Basic Information

Product Name	2-(4-Amino-2-Bromophenyl)Acetic Acid
CAS No.	66949-42-6
Molecular Formula	C8H8BrNO2
Molecular Weight	230.06 g/mol
Synonyms	2-Bromo-4-aminophenylacetic Acid; (4-Amino-2-bromophenyl)acetic Acid; 2-Bromo-4-aminobenzeneacetic Acid; 4-Amino-2-bromobenzeneacetic Acid; α-(4-Amino-2-bromophenyl)acetic Acid; 2-(4-Amino-2-bromophenyl)ethanoic Acid; 66949-42-6; 2-Br-4-NH2-PhAcOH
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for this high-value intermediate. Production follows current Good Manufacturing Practices (cGMP) principles where applicable, and each batch is analyzed against rigorous in-house specifications to ensure consistency and purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.