Description

3-O,4-O,5-o-Trimethyl-1-O,2-o-Isopropylidene-D-Arabino-Hexa-1-Enitol is a high-purity, protected carbohydrate derivative and a key chiral building block in organic synthesis. This compound is essential for researchers and manufacturers requiring precise stereochemistry and functional group manipulation. It is primarily utilized in the pharmaceutical industry for the development of nucleoside analogs, antiviral agents, and other complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside and nucleotide analogs with potential antiviral or anticancer activity.
• Chiral Synthesis: Serves as a versatile chiral pool starting material for constructing complex natural products and active pharmaceutical ingredients (APIs) with defined stereocenters.
• Glycochemistry Research: Used in academic and industrial R&D for studying glycosylation reactions and developing new carbohydrate-based therapeutics and diagnostics.
• Process Chemistry: Employed in scale-up and route development for the efficient, cost-effective production of specialty fine chemicals.
• Bioconjugate Development: Acts as a linker or spacer molecule in the creation of targeted drug delivery systems and antibody-drug conjugates (ADCs).

Basic Information

Item	Detail
Product Name	3-O,4-O,5-o-Trimethyl-1-O,2-o-Isopropylidene-D-Arabino-Hexa-1-Enitol
CAS No.	66851-40-9
Molecular Formula	C12H20O6
Molecular Weight	260.28 g/mol
Synonyms	1,2-O-Isopropylidene-3,4,5-tri-O-methyl-D-arabino-hex-1-enitol; 3,4,5-Tri-O-methyl-1,2-O-isopropylidene-D-arabino-hex-1-enitol; D-Arabino-Hex-1-enitol, 1,2-O-(1-methylethylidene)-3,4,5-tri-O-methyl-; Protected D-Arabinose Derivative; Isopropylidene Arabino-Hexenitol Trimethyl Ether
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our synthetic intermediates. Each batch of 3-O,4-O,5-o-Trimethyl-1-O,2-o-Isopropylidene-D-Arabino-Hexa-1-Enitol is analyzed to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity (by HPLC/NMR), appearance, and specific rotation are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]D20	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.