Description

n-[(2,4,5-Trichlorophenoxy)Acetyl]-L-Threonine Methyl Ester is a specialized synthetic amino acid derivative, primarily utilized as a key chiral building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of bioactive molecules and fine chemicals. It is essential for research and production in the pharmaceutical and agrochemical industries, where precise stereochemistry and functional group compatibility are critical.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), especially in peptide-mimetic and small molecule drug candidates.
• Agrochemical Synthesis: Serves as a building block in the synthesis of advanced herbicides, plant growth regulators, and other crop protection agents, leveraging the phenoxyacetyl moiety.
• Biochemical Research: Used in proteomics and enzymology studies as a modified amino acid substrate to investigate enzyme mechanisms or protein interactions.
• Fine Chemical Production: Employed in the custom synthesis of complex organic compounds for material science and specialty chemical applications.
• Peptidomimetics Development: Integral for creating peptide analogs with enhanced stability or bioavailability for therapeutic applications.

Basic Information

Product Name	n-[(2,4,5-Trichlorophenoxy)Acetyl]-L-Threonine Methyl Ester
CAS No.	66789-90-0
Molecular Formula	C₁₃H₁₄Cl₃NO₅
Molecular Weight	378.61 g/mol
Synonyms	L-Threonine, N-[(2,4,5-trichlorophenoxy)acetyl]-, methyl ester; Methyl N-[(2,4,5-trichlorophenoxy)acetyl]-L-threoninate; (2S,3R)-Methyl 2-[[2-(2,4,5-trichlorophenoxy)acetyl]amino]-3-hydroxybutanoate; N-(2,4,5-Trichlorophenoxyacetyl)threonine methyl ester; (2,4,5-Trichlorophenoxy)acetyl-L-threonine methyl ester; L-Threonine methyl ester, N-[(2,4,5-trichlorophenoxy)acetyl]-; CAS 66789-90-0
EINECS	Contact for details

Quality Control

Our n-[(2,4,5-Trichlorophenoxy)Acetyl]-L-Threonine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (L-isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.