Description

Ethanone, 1-(3-Chloro-2,2-Dimethylcyclopropyl)-, trans- (9Ci) is a specialized cyclopropane derivative ketone, identified by CAS number 66788-38-3, valued for its unique sterically hindered structure. This compound serves as a critical chiral building block and advanced intermediate in the synthesis of complex organic molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity, structurally defined intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly for antiviral, antibacterial, or central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclopropane ring contributes to biological activity and stability.
• Fine Chemical Manufacturing: Serves as a versatile building block for creating complex fragrance and flavor molecules, or specialty polymers.
• Organic Synthesis Research: Employed in academic and industrial R&D for methodology development, asymmetric synthesis, and the construction of strained ring systems.
• Material Science Precursor: Potential use in the synthesis of specialized ligands for catalysis or monomers for advanced polymeric materials.

Basic Information

Product Name	Ethanone, 1-(3-Chloro-2,2-Dimethylcyclopropyl)-, trans- (9Ci)
CAS No.	66788-38-3
Molecular Formula	C7H11ClO
Molecular Weight	146.61 g/mol
Synonyms	trans-1-(3-Chloro-2,2-dimethylcyclopropyl)ethanone; 1-(3-Chloro-2,2-dimethylcyclopropyl)ethanone; 3'-Chloro-2',2'-dimethylcyclopropyl methyl ketone; (1R,3R)-1-(3-Chloro-2,2-dimethylcyclopropyl)ethanone; (1S,3S)-1-(3-Chloro-2,2-dimethylcyclopropyl)ethanone; 66788-38-3; trans-3-Chloro-2,2-dimethylcyclopropyl methyl ketone
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(3-Chloro-2,2-Dimethylcyclopropyl)-, trans- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (trans-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.