Description

2-(2-Trifluoromethylimidazol-4-Yl)Ethylamine 2Hcl is a high-purity, specialized organic intermediate featuring a trifluoromethyl-substituted imidazole core. This compound is valued for its role in the synthesis of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals, where the trifluoromethyl group is a critical pharmacophore enhancing metabolic stability and lipophilicity. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in oncology, CNS, and anti-infective research.
• Agrochemical Synthesis: Used in developing advanced herbicides, fungicides, and insecticides where the CF3 group improves biological activity and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for creating novel ligands in transition metal catalysis and organocatalysis.
• Bioconjugation & Probe Chemistry: The amine functionality allows for conjugation to biomolecules or fluorescent tags for diagnostic and research applications.
• Material Science Research: Incorporated into organic frameworks or polymers to impart specific electronic or surface properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific synthetic projects requiring this unique scaffold.

Basic Information

Product Name	2-(2-Trifluoromethylimidazol-4-Yl)Ethylamine 2Hcl
CAS No.	66675-25-0
Molecular Formula	C6H9Cl2F3N3
Molecular Weight	251.06 g/mol
Synonyms	2-(2-(Trifluoromethyl)-1H-imidazol-4-yl)ethan-1-amine dihydrochloride; 4-(2-Aminoethyl)-2-(trifluoromethyl)imidazole dihydrochloride; 2-(2-Trifluoromethyl-1H-imidazol-4-yl)ethylamine hydrochloride; 2-(2-Trifluoromethyl-4-imidazolyl)ethylamine dihydrochloride; 2-(2-Trifluoromethylimidazol-4-yl)ethanamine 2HCl; 66675-25-0; 2-(2-Trifluoromethyl-1H-imidazol-4-yl)ethanamine dihydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Trifluoromethylimidazol-4-Yl)Ethylamine 2Hcl is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are suitable for research and development under cGMP guidelines for intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and analytical methods (HPLC, NMR) is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.