Description

2-(tert-Butoxy)-2-Phenylacetic Acid is a specialized organic acid ester derivative with significant utility as a versatile synthetic intermediate. Its unique structure, featuring both a protected carboxylic acid group and an aromatic phenyl ring, makes it a valuable building block for constructing complex molecules in advanced chemical synthesis. This compound is primarily sought after by research institutions and industrial R&D departments within the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring protected carboxyl functionalities.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Building Block: Serves as a versatile reagent for introducing the 2-phenylacetic acid moiety under mild, protected conditions in multi-step syntheses.
• Peptide Mimetics Research: Employed in medicinal chemistry for the design and synthesis of peptide analogs and enzyme inhibitors.
• Ligand and Catalyst Development: Useful for creating chiral auxiliaries or complex ligands used in asymmetric catalysis.
• Material Science Precursor: Potential intermediate in the synthesis of specialized monomers for advanced polymers.

Basic Information

Product Name	2-(tert-Butoxy)-2-Phenylacetic Acid
CAS No.	66667-02-5
Molecular Formula	C₁₂H₁₆O₃
Molecular Weight	208.25 g/mol
Synonyms	2-(tert-Butoxy)-2-phenylacetic acid; α-(tert-Butoxy)phenylacetic acid; 2-Phenyl-2-[(2-methyl-2-propanyl)oxy]acetic acid; tert-Butyl phenylglyoxylate hemiacetal; Phenyl(tert-butoxy)acetic acid; 66667-02-5; NSC 403079
EINECS	Contact for details

Quality Control

Our 2-(tert-Butoxy)-2-Phenylacetic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research and scale-up applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.