Description

Di-Boc-3,4-Diaminobenzoic Acid CAS NO 66636-17-7 is a high-purity, protected diamine derivative of benzoic acid, serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a stable, orthogonal protecting group strategy for the sensitive aromatic diamine functionality, enabling precise and complex molecular construction. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing active pharmaceutical ingredients (APIs), ligands, and specialty polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex heterocycles, kinase inhibitors, and other small molecule therapeutics where the protected diamine moiety is required.
• Peptide Mimetics & Conjugation: Used to incorporate rigid, aromatic diamine spacers or linking units into peptide backbones or for bioconjugation strategies.
• Polymer & Material Science: Serves as a monomer or co-monomer for synthesizing specialized polyamides, polyimides, and other high-performance polymers with tailored thermal and mechanical properties.
• Agrochemical Synthesis: Intermediate in the development of novel herbicides, fungicides, and plant growth regulators that utilize diaminobenzoic acid scaffolds.
• Ligand & Catalyst Development: Building block for creating chelating ligands used in catalysis, metal-organic frameworks (MOFs), and sensor materials.
• Research & Development: A versatile reagent in academic and industrial R&D for exploring new synthetic methodologies and constructing molecular libraries.

Basic Information

Product Name	Di-Boc-3,4-Diaminobenzoic Acid
CAS No.	66636-17-7
Molecular Formula	C₁₉H₂₈N₂O₆
Molecular Weight	380.44 g/mol
Synonyms	3,4-Bis[(tert-butoxycarbonyl)amino]benzoic Acid; 3,4-Di-Boc-aminobenzoic Acid; Di-tert-butyl 3,4-diaminobenzoate dicarbonate; 3,4-Diaminobenzoic Acid Di-Boc Derivative; N³,N⁴-Bis(tert-butoxycarbonyl)-3,4-diaminobenzoic Acid; 3,4-Bis(Boc-amino)benzoic Acid; Boc-Protected 3,4-Diaminobenzoic Acid
EINECS	Contact for details

Quality Control

Our Di-Boc-3,4-Diaminobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide Certificates of Analysis (COA) with every shipment, detailing all specification results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.