Description

4-(2,2-Diethoxyethoxy)Toluene is a specialty aromatic ether compound that serves as a valuable protected intermediate in advanced organic synthesis. Its molecular structure, featuring a toluene core linked to a diethoxyethoxy side chain, makes it a versatile building block for introducing functionalized aromatic units. This product is essential for research chemists and process development scientists in the pharmaceutical and fine chemical industries who require high-purity, reliable intermediates for constructing complex molecules. Its controlled reactivity profile allows for selective deprotection and further functionalization under mild conditions.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a functionalized toluene derivative.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators where the aromatic ether moiety is critical for bioactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material or intermediate in the production of organic electronic materials and display components.
• Polymer & Resin Modifier: Incorporated into specialty polymers to modify solubility, flexibility, or thermal properties.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of complex organic dyes and high-performance pigments.
• Flavor & Fragrance Compound Synthesis: Used in the controlled synthesis of aromatic compounds for fragrance applications.
• Cross-coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for biaryl formation.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	4-(2,2-Diethoxyethoxy)Toluene
CAS No.	66614-56-0
Molecular Formula	C₁₃H₂₀O₃
Molecular Weight	224.30 g/mol
Synonyms	1-(2,2-Diethoxyethoxy)-4-methylbenzene; p-Tolyl 2,2-diethoxyethyl ether; 4-Methylphenyl 2,2-diethoxyethyl ether; 2,2-Diethoxyethyl p-tolyl ether; Diethoxyethoxy toluene; Benzene, 1-(2,2-diethoxyethoxy)-4-methyl-; (4-Methylphenoxy)acetaldehyde diethyl acetal
EINECS	Contact for details

Quality Control

Our 4-(2,2-Diethoxyethoxy)Toluene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for demanding synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.