Description

Globotriose is a defined trisaccharide carbohydrate, a key structural unit of globoseries glycosphingolipids. This high-purity reference standard is critical for research and development in glycobiology and diagnostic applications. It is primarily utilized by scientists and manufacturers in the pharmaceutical, biotechnology, and diagnostic reagent sectors for studying cell recognition processes, developing vaccines, and creating advanced analytical tools.

Application

• Glycobiology Research: As a crucial intermediate in the biosynthesis of globoseries glycolipids (e.g., Gb3, Pk antigen), used to study cell-surface interactions, signaling, and adhesion.
• Diagnostic Reagent Development: Serves as a hapten or coating antigen in the production of immunoassays and biosensors for the detection of specific antibodies or for blood group typing.
• Vaccine & Therapeutic Agent Research: Used in the synthesis of neoglycoconjugates for investigating carbohydrate-based vaccines targeting cancers and bacterial infections, particularly Shiga toxin-producing E. coli.
• Enzyme Substrate & Inhibitor Studies: Acts as a substrate for glycosyltransferases and glycosidases to elucidate enzyme mechanisms and screen for potential inhibitors.
• Biochemical Standard: Employed as a pure standard for the calibration of analytical instruments like HPLC and Mass Spectrometry in quality control and metabolic studies.
• Cell Culture & Microbiology: Used in studies to understand host-pathogen interactions, as globotriose is the receptor for certain bacterial toxins.

Basic Information

Product Name	Globotriose
CAS No.	66580-68-5
Molecular Formula	C20H35NO15
Molecular Weight	505.49 g/mol
Synonyms	α-D-Galp-(1→4)-β-D-Galp-(1→4)-D-Glc; Pk Trisaccharide; Gb3 Trisaccharide; Globotriaose; Galα1-4Galβ1-4Glc; 4'-Galactosyllactose; O-α-D-Galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-D-glucopyranose
EINECS	Contact for details

Quality Control

Every batch of Globotriose CAS 66580-68-5 is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Bacterial Endotoxins	< 1.0 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.