Description

Propacetamol is a prodrug of paracetamol (acetaminophen), designed for enhanced solubility and rapid metabolic conversion to the active analgesic and antipyretic agent. This chemical intermediate is crucial for developing advanced pharmaceutical formulations that require improved bioavailability and controlled release profiles. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of injectable and high-potency oral analgesic medications.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of paracetamol prodrug formulations for improved drug delivery.
• Injectable Analgesic Development: Used in research and production of sterile injectable solutions where enhanced solubility of paracetamol is required.
• Prodrug Research: Serves as a model compound in pharmacokinetic and pharmacodynamic studies for prodrug design and metabolism.
• High-Potency Formulations: Employed in the development of advanced oral dosage forms aiming for faster onset of analgesic action.
• Chemical Synthesis Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for quality control and method validation.
• Academic & Industrial R&D: A vital compound for investigating novel drug delivery systems and metabolic pathways in academic and corporate research settings.

Basic Information

Product Name	Propacetamol
CAS No.	66532-85-2
Molecular Formula	C13H18N2O3
Molecular Weight	250.29 g/mol
Synonyms	4-Acetamidophenyl N,N-diethylglycinate; Paracetamol propionate ester; Diethylglycyl p-aminophenol ester; Acetaminophen N,N-diethylglycinate; 4'-Hydroxyacetanilide N,N-diethylglycinate; Pro-Dafalgan; CG 5070
EINECS	Contact for details

Quality Control

Our Propacetamol is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, assay, and impurity profiling, to ensure it meets high-purity standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) detailing all test results are provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 1.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.