Description

Diacerein is a high-purity, small-molecule pharmaceutical active ingredient (API) with significant therapeutic potential. This compound matters for its targeted mechanism of action as an interleukin-1 beta inhibitor, offering a specific approach to managing certain inflammatory conditions. It is primarily needed by pharmaceutical manufacturers and research institutions developing treatments for osteoarthritis and other connective tissue disorders. Our supply ensures the consistent quality and reliability required for critical formulation and clinical research applications.

Application

• Pharmaceutical API: Primary use as the active pharmaceutical ingredient in prescription medications for the symptomatic treatment of osteoarthritis.
• Anti-inflammatory Drug Development: Key intermediate or final compound in R&D for novel therapeutics targeting IL-1β mediated inflammatory pathways.
• Veterinary Medicine: Potential application in developing anti-inflammatory treatments for companion animals, such as dogs with degenerative joint disease.
• Biochemical Research: Used as a reference standard or tool compound in pharmacological studies investigating cartilage metabolism and cytokine regulation.
• Formulation Research: Serves as a model compound in developing advanced drug delivery systems to improve solubility and bioavailability.

Basic Information

Product Name	Diacerein
CAS No.	13739-02-1
Molecular Formula	C19H12O8
Molecular Weight	368.29 g/mol
Synonyms	Diacetyl Rhein; Diacereína; Diacerhein; ART 50; 4,5-Bis(acetyloxy)-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic Acid; Rhein Diacetate; Diacetylrhein; 1,8-Diacetoxy-3-carboxyanthraquinone
EINECS	237-321-1

Quality Control

Our Diacerein is manufactured under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical intermediates and APIs. Quality is assured through rigorous in-process and final release testing, including identity confirmation, purity assays, and impurity profiling. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing compliance with agreed specifications. We support compliance with major pharmacopoeial standards and GMP principles where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to orange-yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.