Description

1-Cyanomethyl-1,2,3,4-tetrahydro-quinoline is a versatile, nitrogen-containing heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a tetrahydroquinoline scaffold and a reactive cyanomethyl group, makes it a critical intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research institutions and industrial R&D departments engaged in pharmaceutical development, agrochemical discovery, and materials science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides due to its bioactive heterocyclic core.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Functional Material Research: Employed in the development of organic semiconductors, light-emitting diodes (OLEDs), and advanced polymers.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Scale-Up: Provides a foundational structure for contract research organizations (CROs) and CDMOs performing custom synthesis for clients.

Basic Information

Product Name	1-Cyanomethyl-1,2,3,4-tetrahydro-quinoline
CAS No.	66487-31-8
Molecular Formula	C11H12N2
Molecular Weight	172.23 g/mol
Synonyms	1-(Cyanomethyl)-1,2,3,4-tetrahydroquinoline; Quinoline, 1,2,3,4-tetrahydro-1-(cyanomethyl)-; 1,2,3,4-Tetrahydro-1-quinolineacetonitrile; 1-(Cyanomethyl)-1,2,3,4-tetrahydroquinoline; 1-Cyanomethyl-1,2,3,4-tetrahydroquinoline; Tetrahydroquinoline-1-acetonitrile
EINECS	Contact for details

Quality Control

Our 1-Cyanomethyl-1,2,3,4-tetrahydro-quinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Light yellow to brown liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Standard Grade)
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.