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4,4-Dimethyloxazolidinium Toluenesulphonate CAS NO 66375-36-8


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CAS No.:66375-36-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4,4-Dimethyloxazolidinium Toluenesulphonate is a specialized organic salt, widely recognized as a versatile building block and reagent in advanced chemical synthesis. Its value lies in its role as a protected form of an amino acid derivative, facilitating complex peptide coupling and chiral synthesis with high efficiency and selectivity. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel organic molecules.

Application

  • Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
  • Peptide Chemistry: Used as a protected amino acid equivalent for peptide coupling reactions, minimizing racemization.
  • Asymmetric Synthesis: Serves as a chiral auxiliary or building block for constructing stereogenic centers in organic molecules.
  • Research & Development: A valuable reagent in academic and industrial R&D labs for methodological studies in organic synthesis.
  • Fine Chemical Production: Employed in the manufacture of specialty chemicals, agrochemical intermediates, and advanced materials.
  • Protecting Group Strategy: The oxazolidinone moiety acts as a protective group for amino and carboxyl functions during multi-step syntheses.

Basic Information

Product Name 4,4-Dimethyloxazolidinium Toluenesulphonate
CAS No. 66375-36-8
Molecular Formula C13H19NO5S
Molecular Weight 301.36 g/mol
Synonyms 4,4-Dimethyl-2-oxazolidinium p-toluenesulfonate; 4,4-Dimethyloxazolidinium Tosylate; 2-Oxazolidinium, 4,4-dimethyl-, 4-methylbenzenesulfonate; 4,4-Dimethyl-2-oxazolidinone p-toluenesulfonate salt; (4,4-Dimethyl-2-oxo-1,3-oxazolidin-3-ium) 4-methylbenzenesulfonate; N-Carboxy anhydride derivative salt; Oxazolidinone tosylate salt
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Quality Control

Our 4,4-Dimethyloxazolidinium Toluenesulphonate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm
Related Substances (HPLC) Total impurities ≤ 2.0%
Solubility Soluble in polar organic solvents (e.g., DMF, DMSO)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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