Description

(3R,5'As)-5-(3-Furanyl)-3',5',5'Aβ,7',8',8'Aβ-Hexahydro-7'β-Methylspiro[Furan-3(2H),6'-[6H]Naphtho[1,8-Bc]Furan]-2,2'(4'H)-Dione is a complex, high-purity spirocyclic organic compound featuring a fused naphthofuran core structure. This compound serves as a critical advanced intermediate in sophisticated organic synthesis, particularly for the development of novel pharmaceutical candidates and specialty fine chemicals. It is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise molecular architecture for creating new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring complex heterocyclic frameworks.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where its unique spiro structure can contribute to novel modes of action.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or host materials in OLED devices due to its rigid, conjugated backbone.
• Asymmetric Catalysis Ligand Synthesis: The complex stereochemistry makes it a potential precursor for chiral ligands or organocatalysts.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic chemistry, including novel cyclization and cross-coupling reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value specialty chemicals for various industrial applications.

Basic Information

Item	Details
Product Name	(3R,5'As)-5-(3-Furanyl)-3',5',5'Aβ,7',8',8'Aβ-Hexahydro-7'β-Methylspiro[Furan-3(2H),6'-[6H]Naphtho[1,8-Bc]Furan]-2,2'(4'H)-Dione
CAS No.	66322-19-8
Molecular Formula	C22H20O5
Molecular Weight	364.39 g/mol
Synonyms	5-(3-Furanyl)-3',5',5'a,7',8',8'a-hexahydro-7'β-methylspiro[furan-3(2H),6'-[6H]naphtho[1,8-bc]furan]-2,2'(4'H)-dione; (3R,5'aS)-5-(3-Furyl)-3',5',5'a,7',8',8'a-hexahydro-7'β-methylspiro[furan-3(2H),6'-[6H]naphtho[1,8-bc]furan]-2,2'(4'H)-dione; Spiro[naphtho[1,8-bc]furan-6(6H),3'-furan]-2,2'(4'H)-dione derivative; CAS 66322-19-8.
EINECS	Contact for details

Quality Control

Our production of (3R,5'As)-5-(3-Furanyl)-3',5',5'Aβ,7',8',8'Aβ-Hexahydro-7'β-Methylspiro[Furan-3(2H),6'-[6H]Naphtho[1,8-Bc]Furan]-2,2'(4'H)-Dione adheres to a strict quality management system. Every batch is characterized and purified using advanced chromatographic techniques (e.g., preparative HPLC) to ensure high chemical and isomeric purity. Identity and purity are confirmed by a suite of analytical methods including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing assay, purity, and identification is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.