Description

3-Bromo-5-Chloro-2-Methoxybenzoic Acid is a high-purity, multi-substituted benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated and methoxylated structure makes it an invaluable intermediate for creating complex molecules with specific electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators, leveraging its halogenated aromatic core.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce complex aromatic motifs.
• Dye and Pigment Intermediate: Utilized in the manufacture of specialized colorants and photographic chemicals.
• Contract Research & Development (CRO/CMO): Supplied to research organizations for custom synthesis projects and library development for high-throughput screening.

Basic Information

Product Name	3-Bromo-5-Chloro-2-Methoxybenzoic Acid
CAS No.	66237-57-8
Molecular Formula	C8H6BrClO3
Molecular Weight	265.49 g/mol
Synonyms	2-Methoxy-3-bromo-5-chlorobenzoic Acid; 5-Chloro-3-bromo-2-methoxybenzoic Acid; Benzoic acid, 3-bromo-5-chloro-2-methoxy-; 3-Bromo-5-chloro-o-anisic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-Chloro-2-Methoxybenzoic Acid is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project requirements. We adhere to cGMP principles where applicable to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.