Description

7-Morpholin-4-Yl-6-Nitroquinazolin-4(3H)-One CAS NO 66234-47-7 is a high-purity, advanced pharmaceutical intermediate belonging to the quinazolinone class of heterocyclic compounds. This compound is of significant commercial interest due to its role as a key synthetic precursor in the development of targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the discovery and synthesis of novel drug candidates, particularly in oncology and kinase inhibitor research.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of potential kinase inhibitors and other biologically active molecules.
• Oncology Research: Serves as a core scaffold for the development of novel anti-cancer compounds targeting specific cellular pathways.
• Chemical Synthesis: Used in academic and industrial R&D for exploring new reactions and creating libraries of quinazolinone derivatives.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme inhibition and understand disease mechanisms at a molecular level.

Basic Information

Product Name	7-Morpholin-4-Yl-6-Nitroquinazolin-4(3H)-One
CAS No.	66234-47-7
Molecular Formula	C₁₂H₁₂N₄O₄
Molecular Weight	276.25 g/mol
Synonyms	6-Nitro-7-morpholino-3,4-dihydroquinazolin-4-one; 7-Morpholino-6-nitro-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 7-morpholino-6-nitro-; 6-Nitro-7-morpholin-4-yl-3H-quinazolin-4-one; 7-Morpholin-4-yl-6-nitro-1H-quinazolin-4-one; 66234-47-7; 7-Morpholino-6-nitroquinazolin-4(3H)-one
EINECS	Contact for details

Quality Control

Our production of 7-Morpholin-4-Yl-6-Nitroquinazolin-4(3H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.