Description

Octahydro-5-Hydroxy-4,7-Methano-1H-Indenecarboxylic Acid is a complex, polycyclic carboxylic acid derivative that serves as a versatile chiral building block and intermediate in advanced organic synthesis. Its unique bridged bicyclic structure with hydroxyl functionality makes it valuable for constructing molecules with specific three-dimensional architectures. This compound is primarily sought by research and development chemists in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Asymmetric Catalyst Ligand Precursor: Used to synthesize complex ligands for transition metal catalysts employed in enantioselective reactions.
• Fine Chemical Synthesis: Serves as a building block for creating specialty chemicals, fragrances, and advanced materials requiring specific stereochemistry.
• Academic & Industrial Research: A valuable compound for methodological studies in organic chemistry, particularly in exploring new cycloaddition and functionalization reactions.

Basic Information

Product Name	Octahydro-5-Hydroxy-4,7-Methano-1H-Indenecarboxylic Acid
CAS No.	66208-42-2
Molecular Formula	C11H16O3
Molecular Weight	196.24 g/mol
Synonyms	5-Hydroxy-1,2,3,3a,4,5,6,7-octahydro-4,7-methano-1H-indene-1-carboxylic acid; 1-Carboxy-5-hydroxy-1,2,3,3a,4,5,6,7-octahydro-4,7-methanoindene; Bicyclo[2.2.1]heptane-2-carboxylic acid, 1-hydroxy-3-methylene- derivative; Hydroxymethanoindene carboxylic acid; (1R,3aS,4R,5R,7S,7aS)-5-Hydroxy-1,2,3,3a,4,5,6,7-octahydro-4,7-methano-1H-indene-1-carboxylic acid (stereoisomer).
EINECS	Contact for details

Quality Control

Our Octahydro-5-Hydroxy-4,7-Methano-1H-Indenecarboxylic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and synthesis applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.