Description

2-[4-(Dimethylamino)Phenyl]-2,3-Dihydro-4(1H)-Quinazolinone is a high-purity, advanced pharmaceutical intermediate with a distinct quinazolinone core structure. This compound is valued for its role as a critical building block in the synthesis of complex organic molecules, particularly in medicinal chemistry. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new therapeutic avenues.
• Agrochemical Development: Serves as a scaffold for creating novel pesticides or herbicides due to its bioactive heterocyclic structure.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex nitrogen-containing heterocycles.
• Dye and Pigment Research: Investigated for applications in functional materials, given the chromophoric properties of its conjugated system.

Basic Information

Product Name	2-[4-(Dimethylamino)Phenyl]-2,3-Dihydro-4(1H)-Quinazolinone
CAS No.	66181-66-6
Molecular Formula	C₁₆H₁₇N₃O
Molecular Weight	267.33 g/mol
Synonyms	2-[4-(Dimethylamino)phenyl]-1,2,3,4-tetrahydro-4-quinazolinone; 2-(4-Dimethylaminophenyl)-1,2,3,4-tetrahydroquinazolin-4-one; 4(1H)-Quinazolinone, 2-[4-(dimethylamino)phenyl]-2,3-dihydro-; N,N-Dimethyl-4-(4-oxo-1,2,3,4-tetrahydroquinazolin-2-yl)aniline; 66181-66-6; Quinazolinone derivative DMAP; Tetrahydroquinazolinone intermediate
EINECS	Contact for details

Quality Control

Our production of 2-[4-(Dimethylamino)Phenyl]-2,3-Dihydro-4(1H)-Quinazolinone adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified against established internal specifications using advanced analytical techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.