Description

Hexadecyl Nicotinate is a high-purity ester derivative of nicotinic acid (Vitamin B3) and cetyl alcohol, offering enhanced lipid solubility and skin penetration. This compound is valued for its role as a stable, long-chain precursor to niacin, facilitating controlled release and improved bioavailability in advanced formulations. It is primarily sought by manufacturers in the cosmetic, personal care, and pharmaceutical industries for developing innovative skincare and topical therapeutic products.

Application

• Cosmetic & Skincare Actives: A key ingredient in anti-aging, moisturizing, and skin barrier repair formulations for its niacinamide-like benefits.
• Topical Pharmaceutical Preparations: Used in creams and ointments designed for dermatological conditions, leveraging its vasodilatory and skin-conditioning properties.
• Hair Care Products: Incorporated into serums and treatments to improve scalp health and promote hair strength.
• Transdermal Delivery Systems: Serves as a penetration enhancer and prodrug for the controlled release of nicotinic acid.
• Functional Cosmeceuticals: Found in products targeting redness reduction, improved skin texture, and enhanced luminosity.
• Research & Development: Utilized in biochemical and pharmacological research as a model compound for studying ester prodrugs and topical bioavailability.

Basic Information

Product Name	Hexadecyl Nicotinate
CAS No.	66170-39-6
Molecular Formula	C22H37NO2
Molecular Weight	347.54 g/mol
Synonyms	Nicotinic Acid Hexadecyl Ester; Cetyl Nicotinate; Palmitoyl Nicotinate; Hexadecyl 3-Pyridinecarboxylate; NSC 334365; Niacin Cetyl Ester; Vitamin B3 Cetyl Ester; 3-Pyridinecarboxylic Acid, Hexadecyl Ester
EINECS	266-155-8

Quality Control

Our Hexadecyl Nicotinate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Quality is verified through a comprehensive suite of analytical tests including HPLC, GC, and spectroscopic methods. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and excessive heat.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.