Description

o-δ-Aminooxybutylhydroxylamine is a specialized bifunctional aminooxy compound with a hydroxylamine moiety, offering unique reactivity for conjugation and derivatization. Its primary value lies in its dual functional groups, which enable it to act as a versatile linker or building block in the synthesis of complex molecules. This chemical is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for the development of novel therapeutics, bioconjugates, and advanced materials. Its structure makes it a critical reagent for creating oxime bonds and other stable linkages under mild conditions.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for targeted drug delivery systems.
• Bioconjugation Reagent: Used for site-specific labeling and crosslinking of proteins, antibodies, and peptides via oxime ligation chemistry.
• Polymer Modification: Acts as a functional monomer or crosslinker to introduce aminooxy groups into polymer backbones for advanced material science applications.
• Chemical Probe Synthesis: Employed in the development of diagnostic tools and molecular probes for biochemical and cellular imaging studies.
• Carbohydrate Chemistry: Utilized in the modification and conjugation of sugars and glycans for glycobiology research.
• Surface Functionalization: Applied to modify surfaces (e.g., chips, nanoparticles) with aminooxy groups for subsequent biomolecule immobilization.

Basic Information

Product Name	o-δ-Aminooxybutylhydroxylamine
CAS No.	66080-74-8
Molecular Formula	C₄H₁₀N₂O₂
Molecular Weight	118.14 g/mol
Synonyms	4-(Aminooxy)butylhydroxylamine; O-(4-Aminobutyl)hydroxylamine; 4-Aminooxy-1-butylhydroxylamine; 1-Aminooxy-4-hydroxyaminobutane; Aminooxybutylhydroxylamine; N-(4-Hydroxyaminobutoxy)amine; 4-(Hydroxyamino)butoxyamine
EINECS	Contact for details

Quality Control

Our o-δ-Aminooxybutylhydroxylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and pharmaceutical-grade intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation, the container should be kept sealed and only opened in a controlled environment to minimize exposure to air.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.