Description

6-Bromo-3-Methylbenzodisoxazole is a high-purity organic heterocyclic compound serving as a versatile and critical building block in advanced chemical synthesis. Its unique fused-ring structure, functionalized with bromine and methyl groups, makes it an essential intermediate for creating complex molecular architectures. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where the benzodisoxazole core contributes to biological activity.
• Material Science Precursor: Serves as a building block for organic electronic materials, including charge-transport materials, OLED (Organic Light-Emitting Diode) emitters, and photoconductive polymers.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs) due to its nitrogen-oxygen heterocyclic structure.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D chemists exploring new heterocyclic chemistry, cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig), and structure-activity relationships (SAR).
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of specialized dyes, fluorescent markers, and high-performance pigments.

Basic Information

Product Name	6-Bromo-3-Methylbenzodisoxazole
CAS No.	66033-69-0
Molecular Formula	C8H6BrNO2
Molecular Weight	228.05 g/mol
Synonyms	6-Bromo-3-methyl-1,2-benzisoxazole; 3-Methyl-6-bromobenzisoxazole; 6-Bromo-3-methylbenzo[d]isoxazole; 1,2-Benzisoxazole, 6-bromo-3-methyl-; 66033-69-0; Bromomethylbenzodisoxazole; 6-Br-3-Me-Benzodisoxazole
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Methylbenzodisoxazole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent lot-to-lot quality. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical specifications. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.