Description

2-Methyl-6-(Trifluoromethyl)Quinoline is a specialized heterocyclic building block featuring a quinoline core substituted with a methyl and a trifluoromethyl group, offering unique electronic and steric properties. This compound is valued for its role as a key intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where the trifluoromethyl group is crucial for modulating lipophilicity and metabolic stability. It is primarily sought by research institutions and industrial manufacturers in the agrochemical, pharmaceutical, and material science sectors for developing novel compounds with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research, where the quinoline scaffold is prevalent.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging the bioactivity of the quinoline structure.
• Material Science Research: Serves as a building block for organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient character.
• Ligand and Catalyst Development: Employed in the design of novel ligands for metal-catalyzed cross-coupling reactions in fine chemical synthesis.
• Fluorinated Compound Library: A valuable substrate for creating diverse fluorinated compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	2-Methyl-6-(Trifluoromethyl)Quinoline
CAS No.	66023-21-0
Molecular Formula	C11H8F3N
Molecular Weight	211.18 g/mol
Synonyms	6-(Trifluoromethyl)-2-methylquinoline; 2-Methyl-6-trifluoromethylquinoline; Quinoline, 2-methyl-6-(trifluoromethyl)-; 2-Methyl-6-(trifluoromethyl)chinolin; 2-Methyl-6-(trifluoromethyl)quinoleine
EINECS	Contact for details

Quality Control

Our 2-Methyl-6-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.