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3-[(Pyridine-1-Oxide)-2-Yl]-1H-Indole-2-Carboxamide CAS NO 65937-70-4


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CAS No.:65937-70-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-[(Pyridine-1-Oxide)-2-Yl]-1H-Indole-2-Carboxamide is a high-purity, specialized heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique molecular architecture, featuring fused pyridine-N-oxide and indole moieties, makes it a valuable precursor for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of potential therapeutic agents targeting various disease pathways.

Application

  • Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, especially in oncology and neurology.
  • Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
  • Chemical Biology Probes: Serves as a starting material for creating molecular probes to study enzyme function and cellular signaling pathways.
  • Agrochemical Development: Potential intermediate in the synthesis of novel crop protection agents and pesticides.
  • Material Science: Investigated for the development of organic semiconductors, ligands for catalysis, or advanced polymers with specific electronic properties.

Basic Information

Product Name 3-[(Pyridine-1-Oxide)-2-Yl]-1H-Indole-2-Carboxamide
CAS No. 65937-70-4
Molecular Formula C15H11N3O2
Molecular Weight 265.27 g/mol
Synonyms 1H-Indole-2-carboxamide, 3-(2-pyridinyl-N-oxide)-; 3-(2-Pyridinyl-N-oxide)-1H-indole-2-carboxamide; 3-(Pyridine-1-oxide-2-yl)-1H-indole-2-carboxamide; 3-(2-Pyridyl-1-oxide)indole-2-carboxamide; 2-Carbamoyl-3-(2-pyridyl-1-oxide)indole; 3-(2-Pyridyl-N-oxide)indole-2-carboxylic acid amide; 3-(Pyridin-2-yl-1-oxide)-1H-indol-2-carboxamid
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Quality Control

Our 3-[(Pyridine-1-Oxide)-2-Yl]-1H-Indole-2-Carboxamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item Specification
Appearance Off-white to light yellow crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 97.0% (Area %)
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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