Description

(1R)-7β-Ethenyl-1,2,3,4,4A,4Bα,5,6,7,9,10,10Aα-Dodecahydro-2β-Hydroxy-1,4Aβ,7-Trimethyl-1α-Phenanthrenemethanol is a high-purity, complex diterpenoid derivative with a sterically defined phenanthrene backbone. This compound matters as a critical advanced pharmaceutical intermediate or reference standard for the research and development of novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block in the multi-step synthesis of complex drug candidates, particularly those with steroidal or terpenoid-like structures.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical research and manufacturing.
• Medicinal Chemistry Research: Serves as a scaffold or precursor for exploring structure-activity relationships (SAR) in the discovery of new bioactive compounds.
• Process Chemistry Development: Employed in route scouting and optimization for the efficient, scalable production of target molecules.
• Academic & Institutional Research: Utilized in university and institutional labs for studies in organic synthesis, natural product chemistry, and chemical biology.
• Custom Synthesis & Contract Manufacturing: A starting material for specialized custom synthesis projects undertaken by CDMOs (Contract Development and Manufacturing Organizations).

Basic Information

Product Name	(1R)-7β-Ethenyl-1,2,3,4,4A,4Bα,5,6,7,9,10,10Aα-Dodecahydro-2β-Hydroxy-1,4Aβ,7-Trimethyl-1α-Phenanthrenemethanol
CAS No.	65894-38-4
Molecular Formula	C20H30O2
Molecular Weight	302.45 g/mol
Synonyms	(1R,2R,4aS,4bR,7S,10aS)-7-Ethenyl-1,2,4a,4b,5,6,7,8,10,10a-decahydro-2-hydroxy-1,4a,7-trimethyl-1-phenanthrenemethanol; 7-Ethenyl-1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahydro-2-hydroxy-1,4a,7-trimethyl-1-phenanthrenemethanol; (1R)-7β-Ethenyl-1,2,3,4,4a,4bα,5,6,7,9,10,10aα-dodecahydro-2β-hydroxy-1,4aβ,7-trimethyl-1α-phenanthrenemethanol; Diterpenoid Alcohol Derivative; Phenanthrenemethanol Derivative
EINECS	Contact for details

Quality Control

Our (1R)-7β-Ethenyl-1,2,3,4,4A,4Bα,5,6,7,9,10,10Aα-Dodecahydro-2β-Hydroxy-1,4Aβ,7-Trimethyl-1α-Phenanthrenemethanol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single impurity	≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.