Description

Tricyclo[2.2.1.02,6]Heptan-3-Ol, 5-Ethynyl-, Stereoisomer (9Ci) is a specialized bicyclic organic compound featuring a unique norbornane skeleton modified with both hydroxyl and ethynyl functional groups. This molecular architecture makes it a valuable and versatile chiral building block for advanced organic synthesis. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex, three-dimensional molecular frameworks. The compound's stereochemistry is critical for applications requiring precise spatial orientation of functional groups.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used in the creation of advanced pesticide and herbicide molecules where the rigid norbornane structure can enhance biological activity and environmental stability.
• Material Science Research: Acts as a monomer or precursor for developing specialty polymers with unique thermal or mechanical properties due to its strained ring system and reactive ethynyl group.
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral auxiliary in catalytic reactions to induce enantioselectivity in the synthesis of fine chemicals.
• Academic & Industrial R&D: A fundamental reagent for methodological studies in organic chemistry, including cycloaddition reactions and ring-opening polymerizations.
• Flavor & Fragrance Chemistry: Potential use as an intermediate for synthesizing complex terpenoid-like aroma compounds with specific olfactory characteristics.

Basic Information

Product Name	Tricyclo[2.2.1.02,6]Heptan-3-Ol, 5-Ethynyl-, Stereoisomer (9Ci)
CAS No.	65831-16-5
Molecular Formula	C9H10O
Molecular Weight	134.18 g/mol
Synonyms	5-Ethynyltricyclo[2.2.1.02,6]heptan-3-ol; 5-Ethynyl-2-norbornanol; 5-Ethynylbicyclo[2.2.1]heptan-2-ol; 5-Ethynyl-endo/endo-norbornanol; 5-Ethynyl-2-hydroxybicyclo[2.2.1]heptane; Ethynyl norbornanol; NSC 403120; Bicyclo[2.2.1]heptane-2-ol, 5-ethynyl-
EINECS	Contact for details

Quality Control

Our Tricyclo[2.2.1.02,6]Heptan-3-Ol, 5-Ethynyl-, Stereoisomer (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high chemical purity, precise stereochemical identity, and consistent lot-to-lot performance. Standard quality parameters include assay by GC/HPLC, chiral purity determination, and control of residual solvents. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry atmosphere to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (specify isomer)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.