Description

4-o-Acetyl-2,5-Anhydro-1,3-o-Isopropylidene-6-o-Trityl-D-Glucitol is a sophisticated, multi-protected carbohydrate derivative, serving as a critical chiral building block and advanced intermediate in synthetic organic chemistry. Its value lies in its precisely defined stereochemistry and protective group pattern, enabling the controlled synthesis of complex molecules with high regio- and stereoselectivity. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing nucleoside analogs, glycosidase inhibitors, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel nucleoside and nucleotide analogs with potential antiviral or anticancer activity.
• Glycoscience Research: Used in the study of glycosylation reactions and the development of glycosidase inhibitors or activators.
• Carbohydrate Chemistry: Serves as a protected precursor for the preparation of rare sugars, C-glycosides, and other complex carbohydrate structures.
• Agrochemical Synthesis: Employed as a building block for creating chiral active ingredients with specific biological functions.
• Process Development: Utilized in route scouting and scale-up for the production of high-value fine chemicals and active pharmaceutical ingredients (APIs).
• Material Science: Potential monomer or precursor for synthesizing chiral polymers or functional materials.

Basic Information

Product Name	4-o-Acetyl-2,5-Anhydro-1,3-o-Isopropylidene-6-o-Trityl-D-Glucitol
CAS No.	65729-83-1
Molecular Formula	C32H36O6
Molecular Weight	516.63 g/mol
Synonyms	1,2:5,6-Di-O-isopropylidene-3-O-trityl-D-glucofuranose; 3-O-Trityl-1,2:5,6-di-O-isopropylidene-α-D-glucofuranose; 1,2:5,6-Di-O-isopropylidene-3-O-triphenylmethyl-α-D-glucofuranose; 3-O-Trityl-1,2:5,6-diisopropylidene-α-D-glucofuranose; D-Glucitol, 4-acetyl-2,5-anhydro-1,3-O-(1-methylethylidene)-6-O-triphenylmethyl-; 3-O-Trt-1,2:5,6-di-O-isopropylidene-α-D-glucofuranose
EINECS	Contact for details

Quality Control

Our 4-o-Acetyl-2,5-Anhydro-1,3-o-Isopropylidene-6-o-Trityl-D-Glucitol is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and optical rotation measurement, to ensure identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Optical Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.