Description

2,2,6,6-Tetramethylpiperidine-4-Carboxylic Acid, Hydrochloride Salt is a high-purity, sterically hindered piperidine derivative that serves as a critical building block and chiral auxiliary in advanced organic synthesis. Its value lies in its ability to impart stereochemical control and modify reaction pathways, making it indispensable for producing complex, high-value molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system.
• Catalyst & Ligand Synthesis: Used to prepare sophisticated ligands and organocatalysts for asymmetric synthesis, enhancing reaction selectivity and yield.
• Agrochemical Research: Employed in the development of novel pesticides and herbicides where specific stereochemistry is required for biological activity.
• Polymer Modification: Acts as a stabilizer precursor or functional monomer to create light-stable and durable high-performance polymers.
• Academic & Process Chemistry: A valuable reagent for methodological development in organic chemistry and scale-up process optimization.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals, flavors, and fragrances requiring precise molecular architecture.

Basic Information

Product Name	2,2,6,6-Tetramethylpiperidine-4-Carboxylic Acid, Hydrochloride Salt
CAS No.	65728-19-0
Molecular Formula	C10H20NO2Cl
Molecular Weight	221.72 g/mol
Synonyms	4-Piperidinecarboxylic acid, 2,2,6,6-tetramethyl-, hydrochloride; Tempo-4-carboxylic acid hydrochloride; 2,2,6,6-Tetramethyl-4-piperidinecarboxylic acid hydrochloride; TMPCA-HCl; 4-Carboxy-2,2,6,6-tetramethylpiperidine hydrochloride; (2,2,6,6-Tetramethylpiperidin-4-yl)carboxylic acid hydrochloride; Proxyl carboxylic acid hydrochloride; 65728-19-0
EINECS	Contact for details

Quality Control

Our 2,2,6,6-Tetramethylpiperidine-4-Carboxylic Acid, Hydrochloride Salt is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and titration, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.