Description

1 2:5 6-Bis-o-(1-Methylethylidene-1L- CAS NO 65556-81-2 is a specialized chemical intermediate characterized by its unique acetal-protected diol structure. This compound matters for its role as a critical building block in advanced organic synthesis, offering a protected form of a vicinal diol that is essential for creating complex molecular architectures. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Serves as a key protected synthon in the multi-step synthesis of complex drug molecules, particularly those requiring stereochemical control.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where its protected diol functionality is crucial for final product activity.
• Fine Chemical Production: Acts as a versatile precursor for catalysts, ligands, and specialty polymers requiring specific hydroxyl group protection.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and material science research.
• Chiral Auxiliary Preparation: Utilized in the synthesis of chiral building blocks for asymmetric synthesis applications.

Basic Information

Product Name	1 2:5 6-Bis-o-(1-Methylethylidene-1L- CAS NO 65556-81-2
CAS No.	65556-81-2
Molecular Formula	C10H18O4
Molecular Weight	202.25 g/mol
Synonyms	1,2:5,6-Di-O-isopropylidene-D-mannitol; Diacetone-D-mannitol; D-Mannitol 1,2:5,6-diacetonide; (2R,3R,4R,5R)-2,2,5,5-Tetramethyl-1,3,4,6-tetroxane; 1,2:5,6-Di-O-(1-methylethylidene)-D-mannitol; Isopropylidene-D-mannitol; D-Mannitol diacetonide
EINECS	265-785-9

Quality Control

Our 1 2:5 6-Bis-o-(1-Methylethylidene-1L- CAS NO 65556-81-2 is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	119 - 123 °C
Specific Rotation [α]20/D	+23.0° to +25.0° (c=1 in H2O)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.