Description

8-Bromo-4-Chloroquinoline is a high-purity halogenated quinoline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual halogen functionality, which provides distinct reactive sites for selective cross-coupling and substitution reactions, enabling the construction of complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of quinoline-based drug candidates, including potential antimalarial, anticancer, and antimicrobial agents.
• Agrochemical Synthesis: Used in the research and production of advanced fungicides, herbicides, and pesticides that leverage the quinoline scaffold.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Research & Development: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and in process chemistry for route scouting and optimization.
• Ligand and Catalyst Preparation: Utilized to synthesize novel nitrogen-containing ligands for transition metal catalysis.
• Fine Chemical Production: Acts as a versatile intermediate for manufacturing specialty chemicals and dyes.

Basic Information

Product Name	8-Bromo-4-Chloroquinoline
CAS No.	65340-71-8
Molecular Formula	C9H5BrClN
Molecular Weight	242.50 g/mol
Synonyms	4-Chloro-8-bromoquinoline; 8-Bromo-4-chloroquinoline; Quinoline, 8-bromo-4-chloro-; 65340-71-8; 8-Br-4-Cl-quinoline
EINECS	Contact for details

Quality Control

Our 8-Bromo-4-Chloroquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet your specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.