Description

Cocaine-D3 100 Ug Per Ml In Acidified Me is a certified reference material (CRM) and analytical standard, specifically a deuterated internal standard of cocaine. This product is essential for ensuring the accuracy, precision, and traceability of quantitative analyses in forensic, clinical, and research laboratories. It is primarily used for method development, calibration, and quality control in mass spectrometry-based assays, providing a critical tool for laboratories requiring definitive identification and quantification of cocaine and its metabolites.

Application

• Quantitative Mass Spectrometry (LC-MS/MS, GC-MS): Serves as a deuterium-labeled internal standard for the precise and accurate quantification of cocaine in complex biological matrices such as urine, blood, plasma, and hair.
• Forensic Toxicology: Critical for confirmatory testing in workplace drug testing, post-mortem analysis, and criminal investigations to meet strict chain-of-custody and legal defensibility requirements.
• Clinical Research & Pharmacokinetics: Used in studies investigating drug metabolism, abuse potential, and the pharmacokinetic profile of cocaine in human subjects.
• Method Development & Validation: Enables scientists to develop, optimize, and validate new analytical methods with high specificity and sensitivity, correcting for matrix effects and instrument variability.
• Laboratory Quality Assurance/Quality Control (QA/QC): Employed in routine laboratory QC protocols to monitor assay performance, ensure compliance with ISO/IEC 17025, and participate in proficiency testing programs.
• Pharmaceutical Impurity Testing: May be utilized in the analysis of pharmaceutical products where cocaine or related tropane alkaloids are present as impurities or degradation products.

Basic Information

Product Name	Cocaine-D3 100 Ug Per Ml In Acidified Me
CAS No.	65266-73-1
Molecular Formula	C₁₇H₁₈D₃NO₄
Molecular Weight	306.36 g/mol (for monoisotopic mass)
Synonyms	(−)-Cocaine-d3; Benzoylmethylecgonine-d3; 3β-Hydroxy-1αH,5αH-tropane-2β-carboxylic Acid Methyl Ester Benzoate-d3; Cocaine Internal Standard; Cocaine-d3 Solution; Cocaine Methyl-d3 Ester; Deuterated Cocaine; [2H3]-Cocaine
EINECS	Contact for details

Quality Control

This certified reference material is produced and analyzed under strict quality management systems. Each batch is characterized using orthogonal analytical techniques, including high-resolution mass spectrometry (HRMS) and quantitative NMR (qNMR), to confirm identity, isotopic purity (D-enrichment), and chemical purity. A comprehensive Certificate of Analysis (COA) is supplied with each unit, providing traceable data on concentration, solvent, uncertainty, and storage conditions. Our quality protocols are designed to support compliance with ISO 17034 (Reference Material Producer) and ISO/IEC 17025 (Testing and Calibration Laboratories) standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. The product is supplied in an acidified methanol solution; ensure proper laboratory ventilation and chemical storage practices for flammable and toxic solvents. For long-term stability, avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow solution
Concentration	100 µg/mL ± 5%
Solvent	Acidified Methanol
Identification (MS)	Conforms to reference spectrum
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 99.0%
Stability	Stable for 24 months when stored as directed

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.