Description

2-Bromo-5,6,7,8-Tetrahydroquinoline-3-Carbonitrile is a versatile brominated heterocyclic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure makes it a critical intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective targets.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with enhanced activity.
• Ligand and Catalyst Development: Serves as a starting material for creating complex chelating ligands and organocatalysts.
• Material Science Research: Building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke molecules for client R&D programs.

Basic Information

Product Name	2-Bromo-5,6,7,8-Tetrahydroquinoline-3-Carbonitrile
CAS No.	65242-28-6
Molecular Formula	C₁₀H₉BrN₂
Molecular Weight	237.10 g/mol
Synonyms	2-Bromo-5,6,7,8-tetrahydroquinoline-3-carbonitrile; 3-Cyano-2-bromo-5,6,7,8-tetrahydroquinoline; 2-Bromo-3-cyano-5,6,7,8-tetrahydroquinoline; 5,6,7,8-Tetrahydro-2-bromoquinoline-3-carbonitrile; Quinoline-3-carbonitrile, 2-bromo-5,6,7,8-tetrahydro-; Bromotetrahydroquinolinecarbonitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-5,6,7,8-Tetrahydroquinoline-3-Carbonitrile is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports development from laboratory to commercial scale under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.