Description

2-Chloro-5,6,7,8-Tetrahydroquinoline-3-Carbonitrile is a versatile heterocyclic building block and key synthetic intermediate. Its molecular structure, featuring a chlorinated tetrahydroquinoline core and a reactive nitrile group, makes it a valuable precursor for constructing complex pharmacophores and functional materials. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold.
• Material Science Research: Serves as a building block for creating advanced organic materials, such as ligands for catalysts or components in organic electronics.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies and the exploration of new chemical spaces.
• Fine Chemical Production: Acts as a specialized intermediate in the multi-step synthesis of complex, high-value fine chemicals and dyes.

Basic Information

Product Name	2-Chloro-5,6,7,8-Tetrahydroquinoline-3-Carbonitrile
CAS No.	65242-27-5
Molecular Formula	C10H9ClN2
Molecular Weight	192.65 g/mol
Synonyms	2-Chloro-5,6,7,8-tetrahydroquinoline-3-carbonitrile; 3-Cyano-2-chloro-5,6,7,8-tetrahydroquinoline; 2-Chloro-1,2,3,4-tetrahydroquinoline-3-carbonitrile; 2-Chloro-3-cyano-5,6,7,8-tetrahydroquinoline; 65242-27-5; Quinoline-3-carbonitrile, 2-chloro-5,6,7,8-tetrahydro-
EINECS	Contact for details

Quality Control

Our 2-Chloro-5,6,7,8-Tetrahydroquinoline-3-Carbonitrile is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.