Description

Benzo(A)Pyrene-7,8-Dione is a high-purity, specialized quinone derivative of the polycyclic aromatic hydrocarbon benzo[a]pyrene. This compound is a critical reference standard and analytical intermediate used in environmental and biochemical research to study metabolic activation pathways and DNA adduct formation. It is essential for laboratories in the pharmaceutical, toxicology, and environmental monitoring sectors requiring precise materials for calibration and investigative studies.

Application

• Analytical Reference Standard: Primary use as a certified standard for the quantification and identification of polycyclic aromatic hydrocarbon (PAH) metabolites in complex matrices via HPLC, GC-MS, or LC-MS.
• Biochemical Research: Key intermediate in studying the metabolic activation of benzo[a]pyrene to its ultimate carcinogenic forms, facilitating research into cancer mechanisms and toxicology.
• Environmental Analysis: Used in method development and validation for detecting and monitoring PAH derivatives and their transformation products in soil, water, and air pollution studies.
• DNA Adduct Studies: Employed in *in vitro* and *in vivo* models to investigate the formation and repair of specific DNA adducts, supporting genotoxicity and mutagenicity research.
• Pharmaceutical Development: Serves as a precursor or model compound in the synthesis and testing of potential chemopreventive agents or enzyme inhibitors targeting PAH metabolism.
• Quality Control & Assurance: Critical for internal QC laboratories in chemical manufacturing to ensure the purity and identity of related PAH compounds and metabolites.

Basic Information

Product Name	Benzo(A)Pyrene-7,8-Dione
CAS No.	65199-11-3
Molecular Formula	C₂₀H₁₀O₂
Molecular Weight	282.30 g/mol
Synonyms	7,8-Dioxo-7,8-dihydrobenzo[a]pyrene; Benzo[a]pyrene-7,8-dione; BP-7,8-dione; 7,8-Benzo[a]pyrenedione; 7,8-Dihydrobenzo[a]pyrene-7,8-dione; B[a]P-7,8-dione; 7,8-Diketobenzo[a]pyrene
EINECS	Contact for details

Quality Control

Every batch of Benzo(A)Pyrene-7,8-Dione is manufactured and analyzed under strict quality management protocols. Our products undergo rigorous quality testing including HPLC purity analysis, identity confirmation (IR, NMR), and impurity profiling to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to Orange Crystalline Powder
Identification (IR)	Conforms to Structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.