Description

n-[3-[(4-Amino-6,7-Dimethoxy-Quinazolin-2-Yl)-Ethyl-Amino]Propyl]-n-Et Hyl-Furan-2-Carboxamide Hydrochloride is a high-purity, synthetically derived quinazoline derivative with significant pharmacological research potential. This compound is valued for its role as a key intermediate or active pharmaceutical ingredient (API) in the development of targeted therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on oncology and signal transduction pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel kinase inhibitors and other targeted cancer therapies.
• Biochemical Research: Used as a reference standard or tool compound in enzymatic assays and cellular studies to investigate specific biological pathways.
• Preclinical Development: Employed in the formulation and testing of new drug candidates during early-stage pharmaceutical development.
• Academic Research: Utilized in university and institutional labs for fundamental research in medicinal chemistry and pharmacology.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	n-[3-[(4-Amino-6,7-Dimethoxy-Quinazolin-2-Yl)-Ethyl-Amino]Propyl]-n-Et Hyl-Furan-2-Carboxamide Hydrochloride
CAS No.	65189-51-7
Molecular Formula	C22H30N6O4 • HCl
Molecular Weight	470.97 g/mol (Free base: 434.51 g/mol)
Synonyms	N-[3-[(4-Amino-6,7-dimethoxy-2-quinazolinyl)ethylamino]propyl]-N-ethyl-2-furancarboxamide hydrochloride; 4-Amino-6,7-dimethoxy-2-[N-ethyl-N-[3-[(N-ethyl-2-furanylcarbonyl)amino]propyl]amino]quinazoline hydrochloride; PD 153035 hydrochloride; EGFR Inhibitor PD153035 HCl; Tyrphostin AG 1517; ZD-1530 hydrochloride; NSC 687852
EINECS	Contact for details

Quality Control

Our n-[3-[(4-Amino-6,7-Dimethoxy-Quinazolin-2-Yl)-Ethyl-Amino]Propyl]-n-Et Hyl-Furan-2-Carboxamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	<20 ppm
Assay (on dried basis)	97.0% - 102.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.