Description

6-Bromo-Quinoline-2-Carbonitrile is a versatile and high-value brominated quinoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular structure, featuring both a bromine substituent and a nitrile group, makes it an essential building block for constructing complex heterocyclic systems. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or acting as fluorescent probes.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its bioactive quinoline core.
• Material Science: Serves as a monomer or functional unit in the creation of organic semiconductors, liquid crystals, and photoactive polymers.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and cyanation transformations to create diverse chemical libraries.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and for exploring new reaction pathways.

Basic Information

Product Name	6-Bromo-Quinoline-2-Carbonitrile
CAS No.	65185-41-3
Molecular Formula	C10H5BrN2
Molecular Weight	233.07 g/mol
Synonyms	2-Cyano-6-bromoquinoline; 6-Bromo-2-quinolinecarbonitrile; 6-Bromoquinoline-2-carbonitrile; Quinoline, 6-bromo-2-cyano-; 6-Bromo-2-cyanoquinoline; 6-Brom-2-chinolincarbonitril (German); 6-ブロモ-2-キノリンカルボニトリル (Japanese)
EINECS	Contact for details

Quality Control

Our 6-Bromo-Quinoline-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.