Description

8-Chloro-2-Quinoxalinol is a versatile heterocyclic building block and key synthetic intermediate of significant importance in advanced organic chemistry. Its unique quinoxaline core functionalized with chloro and hydroxyl groups makes it a critical precursor for the development of pharmaceuticals, agrochemicals, and functional materials. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting infectious diseases, cancer, and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its bioactive quinoxaline scaffold.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as conductive polymers and light-emitting compounds, due to its electron-deficient aromatic system.
• Dye and Pigment Intermediate: Acts as a starting material for the production of specialized quinoxaline-based dyes and colorants.
• Chemical Biology Probe: Utilized in academic and industrial research to develop molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	8-Chloro-2-Quinoxalinol
CAS No.	65180-12-3
Molecular Formula	C8H5ClN2O
Molecular Weight	180.59 g/mol
Synonyms	8-Chloro-2(1H)-quinoxalinone; 8-Chloro-2-hydroxyquinoxaline; 2-Hydroxy-8-chloroquinoxaline; 8-Chloro-quinoxalin-2-ol; 65180-12-3; 8-Chloro-2-quinoxalinone; 8-Chloro-2-oxo-1,2-dihydroquinoxaline
EINECS	Contact for details

Quality Control

Our 8-Chloro-2-Quinoxalinol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.