Description

(Bicyclo[2.2.1]Hepta-2,5-Diene)[(2S,3S)-Bis(Diphenylphosphino)-Butane] Rhodium(I) Perchlorate is a highly specialized organometallic complex of rhodium, prized for its role as a chiral catalyst in asymmetric synthesis. Its value lies in enabling the production of enantiomerically pure compounds, which is critical for the efficacy and safety of advanced pharmaceuticals and fine chemicals. This product is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-performance, stereoselective catalysts.

Application

• Asymmetric Hydrogenation: A premier catalyst for the enantioselective hydrogenation of prochiral olefins, enamides, and ketones, a key step in chiral drug synthesis.
• Pharmaceutical Intermediate Synthesis: Critical for constructing complex, single-enantiomer intermediates for active pharmaceutical ingredients (APIs).
• Fine Chemical Production: Used in the manufacture of high-value chiral flavors, fragrances, and agrochemicals.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis research.
• Process Chemistry Optimization: Employed in scaling up and optimizing catalytic processes for commercial production.

Basic Information

Product Name	(Bicyclo[2.2.1]Hepta-2,5-Diene)[(2S,3S)-Bis(Diphenylphosphino)-Butane] Rhodium(I) Perchlorate
CAS No.	65012-74-0
Molecular Formula	C41H40ClO4P2Rh
Molecular Weight	788.03 g/mol
Synonyms	Rhodium(I) (2,5-Norbornadiene)[(2S,3S)-Bis(diphenylphosphino)butane] Perchlorate; [(2S,3S)-BDP]Rh(NBD)ClO4; (NBD)[(S,S)-Chiraphos]RhClO4; (S,S)-Chiraphos Rhodium(I) (Norbornadiene) Perchlorate; (2S,3S)-(-)-Bis(diphenylphosphino)butane(2,5-norbornadiene)rhodium(I) perchlorate; Rhodium, (2,5-norbornadiene)[(2S,3S)-2,3-bis(diphenylphosphino)butane]-, perchlorate; (S,S)-Chiraphos-Rh(NBD)ClO4
EINECS	Contact for details

Quality Control

Every batch of our chiral rhodium catalyst is produced and tested under strict quality protocols to ensure consistent high performance and enantioselectivity. We provide comprehensive Certificates of Analysis (COA) detailing critical parameters such as chiral purity, rhodium content, and solvent residues. Our quality management system supports traceability and meets the stringent demands of pharmaceutical R&D and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent oxidation and decomposition. Keep away from strong oxidizers and heat sources. The container must be kept tightly sealed in a dry, cool, and well-ventilated place.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Rhodium Content	12.5 - 13.5 %
Solvent Residues (GC)	Meet ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.